Michael MD

No ORCID on file · 2 papers in corpus

article 1999

Stimulation of Aromatase P450 Promoter (II) Activity in Endometriosis and Its Inhibition in Endometrium Are Regulated by Competitive Binding of Steroidogenic Factor-1 and Chicken Ovalbumin Upstream Promoter Transcription Factor to the Same cis-Acting Element

Molecular Endocrinology ·doi:10.1210/mend.13.2.0229

In stromal cells of endometriosis, marked levels of aromatase P450 (P450arom) mRNA and activity are present and can be vigorously stimulated by (Bu)2cAMP or PGE2 to give rise to physiologically significant estrogen biosynthesis. Since eutop…

review 1997

Endocrine disorders associated with inappropriately high aromatase expression

The Journal of steroid biochemistry and molecular biology ·doi:10.1016/s0960-0760(97)80004-0

Aromatase P450 (P450arom) is responsible for conversion of C19 steroids to estrogens in a number of human tissues, such as the placenta, gonads, adipose tissue, skin and the brain. Aromatase expression in human tissues is regulated by use o…