Castro MP

No ORCID on file · 1 paper in corpus

case-report 2015

Successful use of next generation genomic sequencing (NGS)-directed therapy of clear cell carcinoma of the ovary (CCCO) with trametinib and metformin in a patient with chemotherapy-refractory disease

Gynecologic oncology research and practice ·doi:10.1186/s40661-015-0013-2

PURPOSE: Compared to other subtypes of epithelial ovarian cancer, clear cell carcinoma of the ovary bears an ominous reputation for chemotherapy resistance, increased relapse rate, and diminished survival. Among patients with distinct histo…