Marioni RE

The incidence of the vast majority of neurodegenerative, cancer, and metabolic diseases generally increases exponentially with age. In large-scale biobanks, linking time-to-diagnosis information in electronic health records to multiple geno…

BACKGROUND: Children born preterm face elevated risks of neurodevelopmental impairments across domains. Prior studies have relied on expert-imposed typologies within single domains. This study applies statistical learning to a national data…

The circulating proteome offers insights into the biological pathways that underlie disease. Here, we test relationships between 1,468 Olink protein levels and the incidence of 23 age-related diseases and mortality, over 16 years of electro…