Mannermaa A

No ORCID on file · 3 papers in corpus
2023
FinnGen provides genetic insights from a well-phenotyped isolated population.
Nature ·doi:10.1038/s41586-022-05473-8

Population isolates such as those in Finland benefit genetic research because deleterious alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor allele frequency < 5%). These variants survived the founding …

2016
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.
Gynecologic Oncology ·doi:10.1016/j.ygyno.2015.04.034

ObjectiveClinical genetic testing is commercially available for rs61764370, an inherited variant residing in a KRAS 3' UTR microRNA binding site, based on suggested associations with increased ovarian and breast cancer risk as well as with …

2009
Nuclear expression of Snail1 in borderline and malignant epithelial ovarian tumours is associated with tumour progression.
BMC cancer ·doi:10.1186/1471-2407-9-289

BackgroundTranscription factor Snail1 has a central role in induction of epithelial-mesenchymal transition (EMT). The aim of the present study was to elucidate the expression of Snail1 protein during epithelial ovarian tumourigenesis and to…