Michael A. Pezzone

No ORCID on file · 5 papers in corpus · active 2006-2009

Study types

  • article 4
  • review 1

Condition tags

  • chronic_pelvic_pain 3
  • irritable_bowel_syndrome 1
  • interstitial_cystitis 1
review 2009
Cross‐talk and sensitization of bladder afferent nerves
·doi:10.1002/nau.20817

The coordination of pelvic physiologic function requires complex integrative sensory pathways that may converge both peripherally and/or centrally. Following a focal, acute irritative or infectious pelvic insult, these same afferent pathway…

article 2007
Enhanced expression of mast cell growth factor and mast cell activation in the bladder following the resolution of trinitrobenzenesulfonic acid (TNBS) colitis in female rats
·doi:10.1002/nau.20410

AIMS: Chronic pelvic pain disorders often overlap. We have shown that acute colonic irritation can produce acute irritative micturition patterns and acutely sensitize bladder afferent responses to mechanical and chemical stimuli. We hypothe…

article 2006
Colonic irritation in the rat sensitizes urinary bladder afferents to mechanical and chemical stimuli: an afferent origin of pelvic organ cross-sensitization
·doi:10.1152/ajprenal.00395.2005

Chronic pelvic pain (CPP) disorders frequently overlap. We have demonstrated that acute and chronic colonic irritation can lead to neurogenic cystitis. We hypothesize that acute colonic irritation can sensitize urinary bladder afferents to …

article 2006
Convergence of bladder and colon sensory innervation occurs at the primary afferent level
·doi:10.1016/j.pain.2006.09.023

Dichotomizing afferents are individual dorsal root ganglion (DRG) neurons that innervate two distinct structures thereby providing a form of afferent convergence that may be involved in pelvic organ cross-sensitization. To determine the dis…

article 2006
Sensitization of pelvic nerve afferents and mast cell infiltration in the urinary bladder following chronic colonic irritation is mediated by neuropeptides
·doi:10.1152/ajprenal.00162.2006

Irritable bowel syndrome and interstitial cystitis frequently overlap. We have shown that acute colitis sensitizes urinary bladder afferents to both mechanical and chemical stimuli and that chronic colitis similarly produces neurogenic cyst…