Goodman M.T.
No ORCID on file
· 7 papers in corpus
· active 2013-2024
Study types
- article 1
- other 1
Condition tags
- endometriosis 2
- infertility 1
Top journals
- Nature genetics 2
- American journal of human genetics 1
- Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1
- European journal of human genetics : EJHG 1
- Journal of the National Cancer Institute 1
Frequent coauthors
2024
To identify credible causal risk variants (CCVs) associated with different histotypes of epithelial ovarian cancer (EOC), we performed genome-wide association analysis for 470,825 genotyped and 10,163,797 imputed SNPs in 25,981 EOC cases an…
2023
BackgroundThe role of ovulation in epithelial ovarian cancer (EOC) is supported by the consistent protective effects of parity and oral contraceptive use. Whether these factors protect through anovulation alone remains unclear. We explored …
other
2023
Endometriosis is a common condition in women that causes chronic pain and infertility and is associated with an elevated risk of ovarian cancer. We profiled transcriptomes of >370,000 individual cells from endometriomas (n = 8), endometrios…
2022
Polygenic risk scores (PRS) for epithelial ovarian cancer (EOC) have the potential to improve risk stratification. Joint estimation of Single Nucleotide Polymorphism (SNP) effects in models could improve predictive performance over standard…
2015
Genome-wide association studies (GWAS) have identified 12 epithelial ovarian cancer (EOC) susceptibility alleles. The pattern of association at these loci is consistent in BRCA1 and BRCA2 mutation carriers who are at high risk of EOC. After…
article
2013
Combined and interactive effects of environmental and gwas-identified risk factors in ovarian cancer
Background: There are several well-established environmental risk factors for ovarian cancer, and recent genome-wide association studies have also identified six variants that influence disease risk. However, the interplay between such risk…
2013
BackgroundExperimental and epidemiologic evidence have suggested that chronic inflammation may play a critical role in endometrial carcinogenesis.MethodsTo investigate this hypothesis, a two-stage study was carried out to evaluate single-nu…