Corfield EC

No ORCID on file · 2 papers in corpus

other 2025

Genome-wide insights into generalised anxiety using a dimensional symptom severity approach

medRxiv : the preprint server for health sciences ·doi:10.1101/2025.07.10.25331321

We performed a genome-wide association meta-analysis of generalised anxiety symptom severity in 696,563 individuals of European ancestry from 14 cohorts. We identified 82 independent genome-wide significant variants within 76 loci, 41 of wh…

other 2024

Polygenic Scores for Dizygotic Twinning: Insights into the Genetic Architecture of Female Fertility

medRxiv : the preprint server for health sciences ·doi:10.1101/2024.12.02.24318308

Natural dizygotic twinning (DZT) results from hyper-ovulation and is considered an indicator of female fertility. DZT has low polygenicity, with only 0.20% of SNPs estimated to have a nonzero effect. A polygenic score (PGS) for DZT explains…