Zhu DL

ORCID: 0000-0001-9612-4478 · 3 papers in corpus
lab-animal 2025
Long noncoding RNA LINC00339 promotes osteoporosis development via modulating of regulator CDC42 by binding PARP1
Non-coding RNA research ·doi:10.1016/j.ncrna.2025.06.004

BACKGROUND: Osteoporosis is a systemic skeletal disorder characterized by reduced bone mass and microarchitectural deterioration of bone tissue. Our previous investigation provided preliminary evidence that single nucleotide polymorphisms (…

observational 2019
Re-evaluation of the value of sperm morphology in classical in vitro fertilization in a Northeastern Chinese population
The Journal of international medical research ·doi:10.1177/0300060519860324

OBJECTIVE: This study aimed to re-evaluate the clinical value of a 4% cut-off threshold of sperm morphology in in vitro fertilization (IVF) in a cohort of a Northeastern Chinese population. METHODS: A total of 375 IVF cycles that met stric…

lab-animal 2018
An Osteoporosis Risk SNP at 1p36.12 Acts as an Allele-Specific Enhancer to Modulate LINC00339 Expression via Long-Range Loop Formation
American journal of human genetics ·doi:10.1016/j.ajhg.2018.03.001

Genome-wide association studies (GWASs) have reproducibly associated variants within intergenic regions of 1p36.12 locus with osteoporosis, but the functional roles underlying these noncoding variants are unknown. Through an integrative fun…