Crowley WF Jr

No ORCID on file · 4 papers in corpus
2011
Endocrine Reviews ·doi:10.1210/er.2010-0007

A widely dispersed network of hypothalamic GnRH neurons controls the reproductive axis in mammals. Genetic investigation of the human disease model of isolated GnRH deficiency has revealed several key genes crucial for GnRH neuronal ontogen…

2008
Journal of neuroendocrinology ·doi:10.1111/j.1365-2826.2008.01731.x

In order to find novel modulators of gonadotrophin-releasing hormone (GnRH) secretion, genetic tools were employed in patients with idiopathic hypogonadotrophic hypogonadism (IHH). Mutations in a G-protein coupled receptor, GPR54, were iden…

other 2006
Endocrinology ·doi:10.1210/en.2005-1550

The effect of continuous administration of the C-terminal fragment of metastin, the ligand for the G protein-coupled receptor, GPR54, on GnRH-induced LH secretion was examined in three agonadal, juvenile male monkeys whose responsiveness to…

review 1994
Annual review of medicine ·doi:10.1146/annurev.med.45.1.391

GnRH and its analogues have led to exciting new avenues of therapy in virtually every subspecialty of internal medicine as well as in gynecology, pediatrics, and urology. Since their discovery in 1971, it has been demonstrated that GnRH and…