Uterine fibroids, the most common tumors in reproductive-age women, remain without a defined precursor tissue state. Unlike cervical dysplasia preceding cervical cancer, or colonic polyps preceding colorectal malignancy, no equivalent "at-r…
BackgroundLimited evidence is available regarding preferences of women with uterine fibroids (UF) and treating healthcare providers (HCPs) regarding treatment attributes; this evidence could contribute to patient-centered shared decision-ma…
SignificanceUterine fibroids (UFs) can pose a serious health risk to women. UFs are benign tumors that vary in clinical presentation from asymptomatic to causing debilitating symptoms. UF management is limited by our inability to predict UF…
Treatment of heavy menstrual bleeding associated with uterine fibroids (UF) is evolving. Historically, treatment options were limited to predominantly invasive surgery; today, conservative and novel oral medical treatments are widely availa…
• Uterine fibroids are the most common benign tumor to women of reproductive age with no clear pathomechanism. • Current medical therapies are designed to blunt the stimulatory effects of gonadal steroid hormones on uterine fibroids growth.…