Kolodecik TR

No ORCID on file · 2 papers in corpus

2024

Renalase peptides reduce pancreatitis severity in mice.

American journal of physiology. Gastrointestinal and liver physiology ·doi:10.1152/ajpgi.00143.2024

Acute pancreatitis, an acute inflammatory injury of the pancreas, lacks a specific treatment. The circulatory protein renalase is produced by the kidney and other tissues and has potent anti-inflammatory and prosurvival properties. Recombin…

2012

Activation of soluble adenylyl cyclase protects against secretagogue stimulated zymogen activation in rat pancreaic acinar cells.

PloS one ·doi:10.1371/journal.pone.0041320

An early feature of acute pancreatitis is activation of zymogens, such as trypsinogen, within the pancreatic acinar cell. Supraphysiologic concentrations of the hormone cholecystokinin (CCK; 100 nM), or its orthologue cerulein (CER), induce…