Fleischer K

BACKGROUND: Two-port robotic-assisted hysterectomy presents a minimally invasive alternative to traditional multi-port techniques. Although a limited number of cases have been documented in the literature [1,2], the improved articulation an…

ImportanceTreatments for men seeking fertility care are limited. Antioxidant supplements have been widely studied as a new treatment option, but these studies have had conflicting results.ObjectiveTo assess whether treatment of men seeking …

OBJECTIVE: To highlight the presentation and management of a patient with dysmenorrhea caused by an accessory cavitated uterine malformation (ACUM) while also summarizing the current evidence regarding this pathology. DESIGN: Video article…

Bladder endometriosis accounts for 70-85% of urinary tract endometriosis cases. Urinary tract endometriosis occurs in approximately 1% of those living with endometriosis. Underlying aetiology and pathogenesis are not fully understood, but t…

Turner syndrome (TS) affects 50 per 100 000 females. TS affects multiple organs through all stages of life, necessitating multidisciplinary care. This guideline extends previous ones and includes important new advances, within diagnostics a…

BACKGROUND: Endometriosis surgery outcomes have been widely studied, yet heterogeneity in terminology and techniques persist. OBJECTIVES: This study focuses on the perioperative outcomes of a single surgeon using the same structured approa…

BACKGROUND: Several endometriosis classification systems have been proposed and published but the search for a universal language that communicates the complexity, laterality and severity of this disease continues. The authors introduce the…

BACKGROUND: The use of Indocyanine Green (ICG) is well-described in oncology and more recently in benign gynaecological surgery. In this article we describe submucosal transvaginal ICG infiltration caudal to a vaginal endometriotic nodule t…

Objective The aim of this study was to assess inter-rater reliability for components of the Visual-Numeric Endometriosis Scoring System (VNESS). VNESS is a novel system for describing surgical findings in each compartment of the pelvis in a…

BACKGROUND: The inability to have children affects 10% to 15% of couples worldwide. A male factor is estimated to account for up to half of the infertility cases with between 25% to 87% of male subfertility considered to be due to the effec…

Study questionAre there more de novo mutations (DNMs) present in the genomes of children born through medical assisted reproduction (MAR) compared to spontaneously conceived children?Summary answerIn this pilot study, no statistically signi…

STUDY QUESTION: Is a single endometrial scratch prior to the second fresh IVF/ICSI treatment cost-effective compared to no scratch, when evaluated over a 12-month follow-up period? SUMMARY ANSWER: The incremental cost-effectiveness ratio (…

STUDY QUESTION: Does endometrial scratching in women with one failed IVF/ICSI treatment affect the chance of a live birth of the subsequent fresh IVF/ICSI cycle? SUMMARY ANSWER: In this study, 4.6% more live births were observed in the scr…

INTRODUCTION: Infertility is a worldwide problem and about 10%-15% of all couples will be affected by the inability to have children. In approximately 50% of infertile couples, a male factor is involved. Most of the male infertile cases are…

BACKGROUND: In in vitro fertilisation (IVF) with or without intracytoplasmic sperm injection (ICSI), selection of the most competent embryo(s) for transfer is based on morphological criteria. However, many women do not achieve a pregnancy e…

Study questionDo cumulative live birth rates (CLBRs) over multiple IVF/ICSI cycles confirm the low prognosis in women stratified according to the POSEIDON criteria?Summary answerThe CLBR of low-prognosis women is ~56% over 18 months of IVF/…

BACKGROUND: Success rates of assisted reproductive techniques (ART) are approximately 30%, with the most important limiting factor being embryo implantation. Mechanical endometrial injury, also called 'scratching', has been proposed to posi…