Steven Thung

No ORCID on file · 4 papers in corpus · active 2005-2007

Study types

  • article 2
  • review 2

Condition tags

  • endometriosis 4
article 2007
Upstream Stimulatory Factor-2 Regulates Steroidogenic Factor-1 Expression in Endometriosis
Molecular endocrinology (Baltimore, Md.) ·doi:10.1210/me.2006-0302

Local estrogen biosynthesis is a major factor in the pathogenesis of endometriosis. Aberrant expression of steroidogenic acute regulatory protein (StAR) and aromatase in endometriotic tissue leads to an up-regulation of estrogen production.…

review 2005
Aromatase in endometriosis and uterine leiomyomata
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2005.04.012
article 2005
Defect of Stroma-Epithelial Interaction in Endometriosis is Responsible for Lack of Induction of 17β-Hydroxsteroid Dehydrogenase Type 2 by Progesterone
·doi:10.1016/j.fertnstert.2005.07.469
review 2005
Regulation of aromatase expression in estrogen-responsive breast and uterine disease: from bench to treatment
Pharmacological reviews ·doi:10.1124/pr.57.3.6

A single gene encodes the key enzyme for estrogen biosynthesis termed aromatase, inhibition of which effectively eliminates estrogen production. Aromatase inhibitors successfully treat breast cancer and endometriosis, whereas their roles in…