Heikinheimo O

Of women of reproductive age, 6 to 10% are estimated to be affected by endometriosis. Growth of tissue resembling the uterine mucosa outside the uterine cavity often causes severe menstrual pain, chronic pelvic pain and infertility for the …

Mifepristone is a steroidal antiprogestin and antiglucocorticoid acting at the receptor level. The aromatic dimethylaminophenyl side chain in position 11 of the steroid structure is essential for the antagonistic properties of mifepristone.…

Use of standard estrogen-progestin contraception remains problematic in several subgroups of patients (e.g., those in whom exogenous estrogens are contraindicated, such as survivors of hormone-dependent cancer, or patients with endometriosi…