Subash PT

No ORCID on file · 1 paper in corpus

2025

REST missense mutations reveal disrupted Re1 motif binding and co-repressor interactions in uterine fibroids.

Frontiers in bioinformatics ·doi:10.3389/fbinf.2025.1703356

IntroductionThe Re1-Silencing Transcription Factor (REST) is a master regulator of gene silencing, orchestrating transcriptional repression by tethering chromatin-modifying co-repressors to the Re1 motif of target genes. While REST is recog…