Middelberg RP

No ORCID on file · 4 papers in corpus
other 2012
PloS one ·doi:10.1371/journal.pone.0035605

A recent meta-analysis of genome-wide association (GWA) studies identified 95 loci that influence lipid traits in the adult population and found that collectively these explained about 25-30% of heritability for each trait. Little is known …

other 2012
Human molecular genetics ·doi:10.1093/hmg/ddr478

Serum gamma-glutamyl transferase (GGT) activity is a marker of liver disease which is also prospectively associated with the risk of all-cause mortality, cardiovascular disease, type 2 diabetes and cancers. We have discovered novel loci aff…

other 2011
BMC medical genetics ·doi:10.1186/1471-2350-12-123

BACKGROUND: Genome-wide association studies (GWAS) have become a major strategy for genetic dissection of human complex diseases. Analysing multiple phenotypes jointly may improve both our ability to detect genetic variants with multiple ef…

other 2011
Human molecular genetics ·doi:10.1093/hmg/ddr375

Serum butyrylcholinesterase (BCHE) activity is associated with obesity, blood pressure and biomarkers of cardiovascular and diabetes risk. We have conducted a genome-wide association scan to discover genetic variants affecting BCHE activity…