Carrie Rinker‐Schaeffer

No ORCID on file · 4 papers in corpus · active 2015-2020

Study types

  • article 4
article 2020
Omental macrophages secrete chemokine ligands that promote ovarian cancer colonization of the omentum via CCR1
·doi:10.1038/s42003-020-01246-z

The omentum is the most common site of ovarian cancer metastasis. Immune cell clusters called milky spots are found throughout the omentum. It is however unknown if these immune cells contribute to ovarian cancer metastasis. Here we report …

article 2019
Abstract TMIM-076: OMENTAL MACROPHAGES REGULATE OVARIAN CANCER METASTATIC COLONIZATION THROUGH THE CCL6-CCR1 SIGNALING AXIS
·doi:10.1158/1557-3265.ovcasymp18-tmim-076

Abstract BACKGROUND: Metastatic ovarian cancer remains an urgent clinical problem. The homing and invasion of cancer cells into the omental adipose tissue, which is the preferred site of ovarian cancer metastasis, is a critical step in dise…

article 2016
Omental macrophages: Drivers of ovarian cancer metastatic colonization
·doi:10.1016/j.ygyno.2016.04.197
article 2015
In Vivo and Ex Vivo Approaches to Study Ovarian Cancer Metastatic Colonization of Milky Spot Structures in Peritoneal Adipose
·doi:10.3791/52721-v

High-grade serous ovarian cancer (HGSC), the cause of widespread peritoneal metastases, continues to have an extremely poor prognosis; fewer than 30% of women are alive 5 years after diagnosis. The omentum is a preferred site of HGSC metast…