Dohle W

No ORCID on file · 1 paper in corpus
2022
ChemMedChem ·doi:10.1002/cmdc.202200408

2-Difluoromethoxyestratriene derivatives were designed to improve potency and in vivo stability of the drug candidate 2-methoxyestradiol (2ME2). Compound evaluation in vitro against the proliferation of MCF-7 and MDA MB-231 breast cancer ce…