Czene K

No ORCID on file · 5 papers in corpus
2024
Germline copy number variants and endometrial cancer risk.
Human genetics ·doi:10.1007/s00439-024-02707-9

Known risk loci for endometrial cancer explain approximately one third of familial endometrial cancer. However, the association of germline copy number variants (CNVs) with endometrial cancer risk remains relatively unknown. We conducted a …

review 2018
Genetic overlap between endometriosis and endometrial cancer: evidence from cross‐disease genetic correlation and GWAS meta‐analyses
Cancer medicine ·doi:10.1002/cam4.1445

Abstract Epidemiological, biological, and molecular data suggest links between endometriosis and endometrial cancer, with recent epidemiological studies providing evidence for an association between a previous diagnosis of endometriosis and…

2018
Identification of nine new susceptibility loci for endometrial cancer.
Nature communications ·doi:10.1038/s41467-018-05427-7

Endometrial cancer is the most commonly diagnosed cancer of the female reproductive tract in developed countries. Through genome-wide association studies (GWAS), we have previously identified eight risk loci for endometrial cancer. Here, we…

2016
Association of infertility and fertility treatment with mammographic density in a large screening-based cohort of women: a cross-sectional study.
Breast cancer research : BCR ·doi:10.1186/s13058-016-0693-5

BackgroundOvarian stimulation drugs, in particular hormonal agents used for controlled ovarian stimulation (COS) required to perform in vitro fertilization, increase estrogen and progesterone levels and have therefore been suspected to infl…

2016
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.
Gynecologic Oncology ·doi:10.1016/j.ygyno.2015.04.034

ObjectiveClinical genetic testing is commercially available for rs61764370, an inherited variant residing in a KRAS 3' UTR microRNA binding site, based on suggested associations with increased ovarian and breast cancer risk as well as with …