Komm B

No ORCID on file · 3 papers in corpus
lab-animal 2014
Endometriosis impairs bone marrow-derived stem cell recruitment to the uterus whereas bazedoxifene treatment leads to endometriosis regression and improved uterine stem cell engraftment
Endocrinology ·doi:10.1210/en.2013-1977

Endometriosis is a disease defined by the ectopic growth of uterine endometrium. Stem cells contribute to the generation of endometriosis as well as to repair and regeneration of normal endometrium. Here we demonstrate that the selective es…

lab-animal 2014
Treatment with bazedoxifene and conjugated estrogens results in regression of endometriosis in a murine model
Biology of reproduction ·doi:10.1095/biolreprod.113.114165

Bazedoxifene (BZA), a selective estrogen receptor modulator (SERM), inhibits the action of estrogens on endometrial proliferation. Here, we evaluate the effect of a tissue-selective estrogen complex (TSEC) containing BZA and conjugated estr…

lab-animal 2011
Treatment with bazedoxifene, a selective estrogen receptor modulator, causes regression of endometriosis in a mouse model
Endocrinology ·doi:10.1210/en.2010-1010

Endometriosis is a common estrogen-dependent disorder. Medical treatments currently consist of progestins or GnRH agonists; however, neither is fully effective and both entail significant side effects. Selective estrogen receptor (ER) modul…