Doridot L

No ORCID on file · 7 papers in corpus · active 2021-2026

Study types

  • article 4
  • review 2
  • other 1

Condition tags

  • endometriosis 4
  • infertility 2
  • adenomyosis 2
  • chronic_pelvic_pain 1
article 2026
Preconceptional immunomodulation partially corrects pregnancy abnormalities induced by endometriosis in a mouse model, with normalization of transcriptional alterations observed in the developing fetal-maternal interface at the single cell level
·doi:10.64898/2026.01.02.695166

Abstract Endometriosis is a chronic disease of gynaecological origin that affects approximately 10% of women worldwide and has a significant impact on patients’ lives. Women with endometriosis attempting to conceive may experience infertili…

article 2026
Single-nucleus analysis of menstrual fluid highlights gene expression differences in epithelial cells of endometriosis donors
BMC medicine ·doi:10.1186/s12916-026-05020-6

BACKGROUND: Endometriosis is a common complex gynecological condition that is difficult to efficiently diagnose and remains poorly understood. Menstrual fluid provides a non-invasive source of disease-relevant tissue and has been identified…

review 2025
Microbiota insights in endometriosis
Microbiome ·doi:10.1186/s40168-025-02243-2

Endometriosis affects approximately 10% of women of reproductive age and is characterized by the presence of endometrial-like tissue outside the uterine cavity, leading to chronic pelvic pain, infertility, and a significant reduction in qua…

review 2024
An integrated multi-tissue approach for endometriosis candidate biomarkers: a systematic review
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-023-01181-8

Biomarker identification could help in deciphering endometriosis pathophysiology in addition to their use in the development of non invasive diagnostic and prognostic approaches, that are essential to greatly improve patient care. Despite e…

other 2024
Reduced fertility in an adenomyosis mouse model is associated with an altered immune profile in the uterus during the implantation period
Human Reproduction ·doi:10.1093/humrep/dead246

STUDY QUESTION: Does a reduction in fertility and/or systemic immune cell change occur during the early implantation period in a mouse model of adenomyosis? SUMMARY ANSWER: A reduction in fertility was observed in mice with adenomyosis, co…

article 2024
Western diet promotes endometriotic lesion growth in mice and induces depletion of Akkermansia muciniphila in intestinal microbiota
BMC medicine ·doi:10.1186/s12916-024-03738-9

BACKGROUND: Endometriosis, affecting 10% of women in their reproductive years, remains poorly understood. Both individual and environmental unexplained factors are implicated in this heterogenous condition. This study aims to examine the in…

article 2021
Immune cells and Notch1 signaling appear to drive the epithelial to mesenchymal transition in the development of adenomyosis in mice
Molecular human reproduction ·doi:10.1093/molehr/gaab053

The epithelial to mesenchymal transition (EMT) has been implicated in the development of adenomyosis, along with dysregulated immune responses. Inflammation potentially induces Notch signaling, which could promote this EMT. The objective of…