Hofman A — Endo Lab

2026

Effect of transabdominal versus transvaginal cerclage on preterm birth and neonatal outcomes among patients with a history of cervical insufficiency.

American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2025.06.049

BackgroundThe 2020 Multicentre Abdominal vs Vaginal Randomised Intervention of Cerclage trial found that transabdominal cerclage placed via open laparotomy reduces the risk of spontaneous preterm birth before 32 weeks relative to transvagin…

2016

Genome-wide analysis identifies 12 loci influencing human reproductive behavior.

Nature genetics ·doi:10.1038/ng.3698

The genetic architecture of human reproductive behavior-age at first birth (AFB) and number of children ever born (NEB)-has a strong relationship with fitness, human development, infertility and risk of neuropsychiatric disorders. However, …

2016

Genome-wide associations for birth weight and correlations with adult disease.

Nature ·doi:10.1038/nature19806

Birth weight (BW) has been shown to be influenced by both fetal and maternal factors and in observational studies is reproducibly associated with future risk of adult metabolic diseases including type 2 diabetes (T2D) and cardiovascular dis…

2015

New genetic loci link adipose and insulin biology to body fat distribution.

Nature ·doi:10.1038/nature14132

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links…