A gonadotropin-releasing hormone antagonistic composition, which comprises an optionally substituted condensed-bicyclic compound consisting of a homo or hetero 5 to 7 membered ring and a homo or hetero 5 to 7 membered ring is effective a…
The compound of the present invention possesses excellent gonadotropin-releasing hormone antagonizing activity, and is useful for preventing or treating sex hormone-dependent diseases, e.g., sex hormone-dependent cancers (e.g., prostatic ca…
The compound of the present invention possesses excellent gonadotropin-releasing hormone antagonizing activity, and is useful for preventing or treating sex hormone-dependent diseases, e.g., sex hormone-dependent cancers (e.g., prostatic ca…
PCT No. PCT/JP96/01140 Sec. 371 Date Jun. 6, 1996 Sec. 102(e) Date Jun. 6, 1996 PCT Filed Apr. 25, 1996 PCT Pub. No. WO96/34012 PCT Pub. Date Oct. 31, 1996The LH-RH receptor antagonists containing cyclic pentapeptides or salts thereof and n…
The compound of the present invention possesses excellent gonadotropin-releasing hormone antagonizing activity, and is useful for preventing or treating sex hormone-dependent diseases, e.g., sex hormone-dependent cancers (e.g., prostatic ca…
PCT No. PCT/JP97/01434 Sec. 371 Date Aug. 14, 1997 Sec. 102(e) Date Aug. 14, 1997 PCT Filed Apr. 24, 1997 PCT Pub. No. WO97/41126 PCT Pub. Date Nov. 6, 1997The present thienopyridine derivatives and composition having gonadotropin-releasing…
The present thienopyridine derivatives of formula (I) and composition having gonadotropin-releasing hormone antagonistic activity are useful as prophylactic or therapeutic agents for the prevention or treatment of several hormone dependent …
The LH-RH receptor antagonists containing cyclic pentapeptides or salts thereof and novel cyclic pentapeptide or salts thereof are provided. The LH-RH receptor antagonists of the present invention are effective as medicines for preventing a…
The present quinoline derivatives and compositions having gonadotropin-releasing hormone antagonistic activity are useful as propylactics or therapeutic agent for the prevention or treatment of several hormone dependent diseases, for exampl…
The present thienopyrimidine derivatives and compositions having gonadotropin-releasing hormone antagonistic activity are useful as propylactics or therapeutic agents for the prevention or treatment of several hormone dependent diseases, fo…
The present thienopyrimidine derivatives of formula (I) and compositions having ganodotropin-releasing hormone antagonistic activity are useful as propylactics or therapeutic agents for the prevention or treatment of several hormone depende…
A gonadotropin-releasing hormone antagonistic composition, which comprises an optionally substituted condensed-bicyclic compound consisting of a homo or hetero 5 to 7 membered ring and a homo or hetero 5 to 7 membered ring such as compounds…
PROBLEM TO BE SOLVED: To obtain an antagonist, a new cyclic pentapeptide (salt), having a specific amino acid sequence, presenting LH-RH receptor antagonistic action, thus useful for preventing and treating e.g. prostate cancer, uterine can…
The present thienopyrimidine derivatives of formula (I) and compositions having ganodotropin-releasing hormone antagonistic activity are useful as propylactics or therapeutic agents for the prevention or treatment of several hormone depende…
The present thienopyridine derivatives of formula (I) and composition having gonadotropin-releasing hormone antagonistic activity are useful as prophylactic or therapeutic agents for the prevention or treatment of several hormone dependent …
A thienopyrimidine derivative of formula (I) is effective as a prophylactic or therapeutic agent for the prevention or treatment of several hormone dependent diseases, for example, a sex hormone dependent cancer (e.g. prostatic cancer, canc…
The LH-RH receptor antagonists containing cyclic pentapeptides or salts thereof and novel cyclic pentapeptide or salts thereof are provided. The LH-RH receptor antagonists of the present invention are effective as medicines for preventing a…
A thienopyrimidine derivative of formula (I) is effective as a prophylactic or therapeutic agent for the prevention or treatment of several hormone dependent diseases, for example, a sex hormone dependent cancer (e.g. prostatic cancer, canc…
A gonadotropin-releasing hormone antagonistic composition, which comprises an optionally substituted condensed-bicyclic compound consisting of a homo or hetero 5 to 7 membered ring and a homo or hetero 5 to 7 membered ring such as compounds…