Shafrir AL

No ORCID on file · 30 papers in corpus
observational 2018
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology ·doi:10.1158/1055-9965.epi-17-0609

Background: One model of ovarian cancer development model divides tumors into two types. Type I tumors are characterized by KRAS and BRAF mutations, which can activate mitogen-activated protein kinase (MAPK). Type II tumors are characterize…

review 2018
Best practice & research. Clinical obstetrics & gynaecology ·doi:10.1016/j.bpobgyn.2018.06.001

Endometriosis affects approximately 10% of women of reproductive age. Characteristics robustly associated with a greater risk for endometriosis include early age at menarche, short menstrual cycle length, and lean body size, whereas greater…

observational 2017
Cancer causes & control : CCC ·doi:10.1007/s10552-017-0876-0

PURPOSE: Oral contraceptives (OCs) have been consistently associated with a reduced ovarian cancer risk; however, most previous studies included women in older birth cohorts using high-dose OC formulations. We assessed OC use, including typ…

observational 2016
British journal of cancer ·doi:10.1038/bjc.2016.316

BACKGROUND: Ovarian cancer survival is poor, particularly for platinum-resistant cases. The previous literature on pre-diagnostic reproductive factors and ovarian cancer survival has been mixed. Therefore, we evaluated pre-diagnostic reprod…

observational 2016
Gynecologic Oncology ·doi:10.1016/j.ygyno.2016.09.024

OBJECTIVE: We assessed the association between reproductive and hormonal factors and ovarian cancer incidence characterized by estrogen receptor-α (ERα) and progesterone receptor (PR) status. METHODS: Tissue microarrays were used to assess…