Enrico Gillio Tos

No ORCID on file · 2 papers in corpus

article 2015

Bentamapimod (JNK Inhibitor AS602801) Induces Regression of Endometriotic Lesions in Animal Models

Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115600553

Endometriosis is an estrogen (ER)-dependent gynecological disease caused by the growth of endometrial tissue at extrauterine sites. Current endocrine therapies address the estrogenic aspect of disease and offer some relief from pain but are…

article 2008

Interruption of Inflammatory Pathways with JNK Inhibitors Induces Regression of Human Endometriotic Lesions and Restores Progesterone Receptor Sensitivity in Endometrium and Lesions.

·doi:10.1093/biolreprod/78.s1.113b

Endometriosis is one of the most common causes of chronic pelvic pain, which affects over 70 million adult and adolescent women worldwide. The pathophysiology of endometriosis involves endocrine, inflammatory and angiogenic components and t…