Rogers-Broadway KR

No ORCID on file · 2 papers in corpus

article 2018

Differential expression of mTOR components in endometriosis and ovarian cancer: Effects of rapalogues and dual kinase inhibitors on mTORC1 and mTORC2 stoichiometry

International journal of molecular medicine ·doi:10.3892/ijmm.2018.3967

Endometriosis is a well‑known risk factor for ovarian cancer. The genetic changes that characterise endometriosis are poorly understood; however, the mechanistic target of rapamycin (mTOR) pathway is involved. In this study, we investigated…

2016

Differential effects of rapalogues, dual kinase inhibitors on human ovarian carcinoma cells in vitro.

International journal of oncology ·doi:10.3892/ijo.2016.3531

Ovarian cancer is the second most common gynaecological malignancy and was diagnosed in over 7,000 women in 2011 in the UK. There are currently no reliable biomarkers available for use in a regular screening assay for ovarian cancer and due…