Lynnette A. Ruiz

No ORCID on file · 9 papers in corpus · active 2007-2017

Study types

  • article 8
  • other 1

Condition tags

  • endometriosis 9
  • mesh:D004715 5
  • infertility 5
  • chronic_pelvic_pain 1
article 2017
Pharmacological blockage of the CXCR4-CXCL12 axis in endometriosis leads to contrasting effects in proliferation, migration, and invasion†
Biology of reproduction ·doi:10.1093/biolre/iox152

High levels of inflammatory factors including chemokines have been reported in peritoneal fluid and blood of women with endometriosis. CXCL12 mediates its action by interaction with its specific receptor, CXCR4, reported to be elevated in h…

article 2015
Dysregulation of Lysyl Oxidase Expression in Lesions and Endometrium of Women With Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115585144
article 2011
Single-nucleotide polymorphisms in the lysyl oxidase-like protein 4 and complement component 3 genes are associated with increased risk for endometriosis and endometriosis-associated infertility
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.06.001
article 2010
Association Between Single Nucleotide Polymorphisms and Endometriosis and Endometriosis-Associated Infertility.
·doi:10.1093/biolreprod/83.s1.411

Endometriosis is considered a multifactorial disease influenced by genetic predisposition, deficient immune system and environmental factors. The most common symptoms are chronic pelvic pain and infertility. The pathophysiological mechanism…

article 2010
Basal and Steroid Hormone-Regulated Expression of CXCR4 in Human Endometrium and Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719110379920
article 2009
Basal and Steroid Hormone-Regulated Expression of CXCR4 and CXCL12 in Human Endometrium and Endometriosis.
·doi:10.1093/biolreprod/81.s1.358

Endometriosis is a gynecological disease characterized by the presence of stroma and epithelial cells outside the uterine cavity, causing pain and infertility. This disease is estrogen-dependent and is associated with the activation of infl…

article 2008
Lysyl oxidase is differentially expressed in women with endometriosis-associated infertility compared to fertile women
·doi:10.1016/j.fertnstert.2008.07.257
other 2007
Molecular profiling of experimental endometriosis identified gene expression patterns in common with human disease
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.07.1550

OBJECTIVE: To validate a rat model of endometriosis using complimentary DNA (cDNA) microarrays by identifying common gene expression patterns between experimental and natural disease. DESIGN: Autotransplantation rat model. SETTING: Medica…

article 2007
SENSITIVITY AND SPECIFICITY OF POTENTIAL BLOOD BIOMARKERS FOR ENDOMETRIOSIS
·doi:10.1093/biolreprod/77.s1.211b

Endometriosis is a common, incurable gynecologic disease of unknown etiology, which causes incapacitating pain during menses and infertility. There are no specific non-invasive diagnostic tests for endometriosis, therefore diagnosis is curr…