Akkar OB

No ORCID on file · 3 papers in corpus
lab-animal 2016
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2015.12.013

OBJECTIVE: Currently, medical and surgical treatment options for endometriosis are limited due to suboptimal efficacy, and also safety and tolerance issues. Long-term use of gonadotrophin-releasing hormone analogs, androgenes, and the danaz…

other 2015
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115584448

We aimed to compare the effects of pazopanib, sunitinib, and sorafenib on endometriotic tissue morphology and histological characteristics as well as ovarian reserve in a rat model. Experimental endometriosis was established in 32 rats. The…

lab-animal 2012
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719112452941

Blood vessels are necessary for development and maintenance of the endometriosis and blood flow supplies oxygen and essential nutrient to the disease. Local angiogenesis is regulated by vascular endothelial growth factor (VEGF) and inhibito…