Wise LA

Discrimination may increase risk of spontaneous abortion (SAB, pregnancy loss <20 weeks' gestation) through physiological responses and limited access to resources. We examined associations between self-reported experiences of discriminatio…

BACKGROUND: Orgasm can be an important component of sexual wellbeing broadly and specifically in the preconception period, yet epidemiologic research on orgasm is limited. METHODS: We used cross-sectional data from Pregnancy Study Online (…

ObjectiveNeighborhood disadvantage is associated with adverse reproductive health outcomes, but its association with menstrual disturbances is understudied. Our objective was to estimate the association between neighborhood socioeconomic di…

BACKGROUND: Oil and gas development-a highly prevalent industry in North America-is often located near residential communities. This industry produces a complex mixture of pollutants that may impact human health. Despite well-documented ass…

BACKGROUND: Use of chemical hair straighteners ("relaxers") is associated with higher risks of hormonally mediated conditions. We hypothesized users of relaxers would have a higher prevalence of abnormal uterine bleeding (AUB) and dysmenorr…

BACKGROUND: Female sexual function is important for sexual well-being, general health, fertility, and relationship satisfaction. Distressing impairments in sexual function, clinically recognized as female sexual dysfunction (FSD), can manif…

Bola Grace and colleagues argue that using digital health technologies ethically can increase the scope and scale of research and connect systems to improve women’s health

BACKGROUND: Female sexual function is important for positive sexual expression, relationship satisfaction, and overall health and wellbeing. Female sexual dysfunction (FSD), which affects ∼40% of premenopausal women, may manifest as issues …

OBJECTIVE: To assess whether exposure to lower-chlorinated PCBs from building materials is associated with increased incidence of UL, endometriosis, and PCOS in female residents. METHODS: We studied 21,619 residents of two Danish partially…

BACKGROUND: Fertility success among mixed-sex couples often depends on frequency and timing of sexual intercourse, yet little research has evaluated the association between preconception sexual function and time-to-pregnancy. OBJECTIVE: To…

The health of prospective parents before conception (i.e., preconception health) has important intergenerational consequences. Although oral health is associated with several reproductive outcomes, it is often absent from preconception heal…

INTRODUCTION: Menstrual health is a key patient-reported outcome beyond its importance as a general indicator of health and fertility. However, menstrual function was not measured in the clinical trials of COVID-19 vaccines. The purpose of …

ObjectiveTo use self-reported preconception data to derive models that predict the risk of miscarriage.DesignProspective preconception cohort study.SettingNot applicable.PatientsStudy participants were female, aged 21-45 years, residents of…

BACKGROUND: Black women and people with uteri have utilized collectivistic and relational practices to improve health outcomes in the face of medical racism and discrimination for decades. However, there remains a need for interventions to …

Objective: To compare 12-month post-treatment health-related quality of life (HR-QoL) and symptom severity (SS) changes among patients with symptomatic uterine fibroids (SUF) not seeking fertility and undergo a hysterectomy, abdominal myome…

RESEARCH QUESTION: Are gravidity, parity and breastfeeding history associated with anti-Müllerian hormone concentration among African-American women of reproductive age? DESIGN: This study included baseline data from the Study of the Envir…

BACKGROUND: Metals may influence reproductive health, but few studies have investigated correlates of metal body burden among reproductive-aged women outside of pregnancy. Furthermore, while there is evidence of racial disparities in exposu…

OBJECTIVES: To evaluate the association between preconception contraceptive use and miscarriage. DESIGN: Prospective cohort study. SETTING: Residents of the United States of America or Canada, recruited from 2013 until the end of 2022. P…

ObjectiveTo evaluate the association between seasonal influenza vaccination and miscarriage using data from an ongoing, prospective cohort study.MethodsWe analyzed 2013-2022 data from PRESTO (Pregnancy Study Online), a prospective prepregna…

BACKGROUND: Despite the high prevalence of female sexual dysfunction in population-based studies and the importance of sexual functioning for mixed-sex couples attempting conception, little is known about female sexual function in the preco…

Background: Quality of life (QOL) and psychological health has been reported to be decreased among women with gynecological conditions such as uterine fibroids (UFs). Materials and Methods: Women enrolled in the Comparing Options for Manage…

PURPOSE: To evaluate the relationships among history of asthma, asthma severity, and spontaneous abortion (SAB). METHODS: Pregnancy Study Online is a preconception cohort study of North American couples. During the preconception period, fe…

BACKGROUND: Infertility affects up to 15% of couples. In vitro fertilization (IVF) treatment has modest success rates and some factors associated with infertility and poor treatment outcomes are not modifiable. Several studies have assessed…

STUDY QUESTION: Can we derive adequate models to predict the probability of conception among couples actively trying to conceive? SUMMARY ANSWER: Leveraging data collected from female participants in a North American preconception cohort s…

BACKGROUND: Refusal to participate in studies related to sexual health can compromise the internal and external validity of findings. Research examining non-response to sexual health studies has primarily focused on predictors such as speci…