To identify credible causal risk variants (CCVs) associated with different histotypes of epithelial ovarian cancer (EOC), we performed genome-wide association analysis for 470,825 genotyped and 10,163,797 imputed SNPs in 25,981 EOC cases an…
BackgroundInflammation may contribute to subfertility but this has not been well-explored in large prospective cohort studies.MethodsWe conducted a prospective 12-month cohort study of time to pregnancy in North Carolina, the Time to Concei…
Polygenic risk scores (PRS) for epithelial ovarian cancer (EOC) have the potential to improve risk stratification. Joint estimation of Single Nucleotide Polymorphism (SNP) effects in models could improve predictive performance over standard…
Study questionIs preconception vitamin D level associated with the risk of miscarriage?Summary answerPreconception vitamin D levels are not associated with the risk of miscarriage in a population of women conceiving naturally.What is known …