Maria Cátira Bortolini

No ORCID on file · 2 papers in corpus

observational 2015

Genetic Variations in the TP53 Pathway in Native Americans Strongly Suggest Adaptation to the High Altitudes of the Andes

PloS one ·doi:10.1371/journal.pone.0137823

The diversity of the five single nucleotide polymorphisms located in genes of the TP53 pathway (TP53, rs1042522; MDM2, rs2279744; MDM4, rs1563828; USP7, rs1529916; and LIF, rs929271) were studied in a total of 282 individuals belonging to Q…

review 2012

The TP53 fertility network

Genetics and molecular biology ·doi:10.1590/s1415-47572012000600008

The TP53 gene, first described in 1979, was identified as a tumor suppressor gene in 1989, when it became clear that its product, the p53 nuclear phosphoprotein, was frequently inactivated in many different forms of cancers. Nicknamed "guar…