Kissin DM

ImportanceUse of assisted reproductive technology (ART) has been associated with increased risks for birth defects. Variations in birth defect risks according to type of ART procedure have been noted, but findings are inconsistent.Objective…

ObjectiveTo explore whether recently enacted infertility mandates including coverage for assisted reproductive technology (ART) treatment in New Jersey (2001) and Connecticut (2005) increased ART use, improved embryo transfer practices, and…

ObjectiveTo assess treatment and pregnancy/infant-associated medical costs and birth outcomes for assisted reproductive technology (ART) cycles in a subset of patients using elective double embryo (ET) and to project the difference in costs…

BackgroundLimited published data exist detailing outcomes of donor embryo cycles. Patients and clinicians would benefit from information specific to donor embryo cycles to inform fertility treatment options, counselling, and clinical decisi…

ObjectiveTo investigate the associations among underweight body mass index (BMI), pregnancy, and obstetric outcomes among women using assisted reproductive technology (ART).DesignRetrospective cohort study using national data and log binomi…

ObjectiveTo characterize risks for early pregnancy loss after fresh and frozen IVF cycles and to investigate whether risk is modified by infertility diagnoses or transfer of embryos in fresh versus frozen cycles.DesignRetrospective cohort s…

ObjectiveTo assess the characteristics of IVF cycles for which preimplantation genetic diagnosis (PGD) was used and to evaluate indications for PGD and treatment outcomes associated with this procedure as compared with cycles without PGD wi…

BackgroundResearch has shown an association between assisted reproductive technology (ART) and adverse birth outcomes. We identified whether birth outcomes of ART-conceived pregnancies vary across states with different maternal characterist…

ObjectiveTo evaluate trends and reproductive outcomes of gestational surrogacy in the United States.DesignRetrospective cohort study.SettingInfertility clinics.Patient(s)IVF cycles transferring at least one embryo.Intervention(s)Use of a ge…

Study questionAre assisted reproductive technology (ART) treatment factors or infertility diagnoses associated with autism among ART-conceived children?Summary answerOur study suggests that the incidence of autism diagnosis in ART-conceived…

ObjectiveTo use linked assisted reproductive technology (ART) surveillance and birth certificate data to compare ET practices and perinatal outcomes for a state with a comprehensive mandate requiring coverage of IVF services versus states w…

ObjectiveTo assess endometriosis-associated infertility trends among assisted reproductive technology (ART) cycles, and to compare cancellation and hyperstimulation risks and pregnancy and live birth rates among women using ART for endometr…

ObjectiveTo assess national trends in ectopic pregnancy incidence among assisted reproductive technology users and identify risk factors associated with ectopic pregnancy.MethodsWe identified 553,577 pregnancies reported to the National ART…

ObjectiveTo evaluate trends of monozygotic twinning after single embryo transfer and its association with patient and treatment factors.MethodsOur retrospective cohort study included 28,596 pregnancies after fresh, nondonor single embryo tr…

ImportanceIntracytoplasmic sperm injection (ICSI) is increasingly used in patients without severe male factor infertility without clear evidence of a benefit over conventional in vitro fertilization (IVF).ObjectiveTo assess national trends …

ObjectiveTo assess trends and outcomes of assisted hatching among assisted reproductive technology (ART) cycles.DesignRetrospective cohort analysis using National ART Surveillance System (NASS) data.SettingU.S. fertility centers reporting t…

ObjectiveTo assess the association between number of embryos transferred and a measure of assisted reproductive technology success that emphasizes good perinatal outcome.MethodsWe analyzed assisted reproductive technology cycles initiated i…

ImportanceThe prevalence of oocyte donation for in vitro fertilization (IVF) has increased in the United States, but little information is available regarding maternal or infant outcomes to improve counseling and clinical decision making.Ob…