Riggs MM

No ORCID on file · 3 papers in corpus
2015
FDA Advisory Meeting Clinical Pharmacology Review Utilizes a Quantitative Systems Pharmacology (QSP) Model: A Watershed Moment?
CPT: pharmacometrics & systems pharmacology ·doi:10.1002/psp4.20

In the evolving discipline of quantitative systems pharmacology (QSP), QSP model (QSPM) applications are expanding. Recently, a QSPM was used by US Food and Drug Administration (FDA) clinical pharmacologists to evaluate the appropriateness …

article 2012
Integrated Pharmacometrics and Systems Pharmacology Model‐Based Analyses to Guide GnRH Receptor Modulator Development for Management of Endometriosis
CPT: pharmacometrics & systems pharmacology ·doi:10.1038/psp.2012.10

Endometriosis is a gynecological condition resulting from proliferation of endometrial-like tissue outside the endometrial cavity. Estrogen suppression therapies, mediated through gonadotropin-releasing hormone (GnRH) modulation, decrease e…

2012
Predicting nonlinear changes in bone mineral density over time using a multiscale systems pharmacology model.
CPT: pharmacometrics & systems pharmacology ·doi:10.1038/psp.2012.15

A mathematical model component that extends an existing physiologically based multiscale systems pharmacology model (MSPM) of calcium and bone homeostasis was developed, enabling prediction of nonlinear changes in lumbar spine bone mineral …