Vincenzo Davide Aloi

No ORCID on file · 3 papers in corpus · active 2022-2023

Study types

  • other 2
other 2023
Clotrimazole-Based Modulators of the TRPM3 Ion Channel Reveal Narrow Structure-Activity Relationship
ACS chemical biology ·doi:10.1021/acschembio.2c00672

TRPM3 is an ion channel that is highly expressed in nociceptive neurons and plays a key role in pain perception. In the presence of the endogenous TRPM3 ligand, pregnenolone sulfate (PS), the antifungal compound clotrimazole (Clt) augments …

other 2023
TRPM3 as a novel target to alleviate acute oxaliplatin-induced peripheral neuropathic pain
Pain ·doi:10.1097/j.pain.0000000000002906

Chemotherapy-induced peripheral neuropathic pain (CIPNP) is an adverse effect observed in up to 80% of patients of cancer on treatment with cytostatic drugs including paclitaxel and oxaliplatin. Chemotherapy-induced peripheral neuropathic p…

2022
Pharmacological properties of TRPM3 isoforms are determined by the length of the pore loop.
British journal of pharmacology ·doi:10.1111/bph.15223