Qiao J

BACKGROUND: Trends toward earlier age at menarche, the starting point in women’s reproductive lifespan, have been observed globally. Whether an earlier age at menarche influences Anti-Müllerian hormone (AMH), a clinical indicator of ovarian…

BackgroundIn assisted reproductive technology (ART) laboratories, semen processing is traditionally performed using manual density gradient centrifugation (DGC), which is labor intensive, time consuming, and subject to inter-technician vari…

BACKGROUND: Aspartame, a widely used artificial sweetener, has been implicated in multiple toxicities. However, its potential reproductive toxicity mechanisms remain unclear. This study aimed to investigate the underlying relationship betwe…

BACKGROUND: In vitro maturation (IVM) presents a potential alternative to conventional IVF for special subgroups of infertile couples. Anti-Müllerian Hormone (AMH) is widely regarded as the most robust biomarker for assessing ovarian reserv…

BackgroundHydrosalpinx affects 10-30% of infertile women, creating a hostile tubal microenvironment that impairs embryonic development. Although fluid embryotoxicity is recognised, specific toxic metabolites and their molecular mechanisms r…

BackgroundEnvironmental exposure to trace and heavy metals may influence female fertility, yet their impact on assisted reproductive outcomes remains poorly defined. Maternal diet can potentially modulate metal-related toxicity by influenci…

BackgroundNatural cycle in vitro fertilization (NC-IVF) represents a convenient and safe assisted reproductive technology, making it particularly advantageous for patients with poor ovarian response (POR). This research evaluates the effect…

BackgroundOocyte vitrification, a widely utilized assisted reproductive technology for fertility preservation, can address emergencies arising from the unavailability of sperm from the male partner on the day of oocyte retrieval. However, t…

Ectopic pregnancy (EP) is a common yet fatal complication of in vitro fertilization-embryo transfer (IVF-ET) and intracytoplasmic sperm injection (ICSI). We aim to establish and validate a nomogram in patients undergoing double fresh cleava…

Polycystic ovary syndrome (PCOS) is a prevalent gynecologic endocrine disorder characterized by menstrual irregularities, elevated androgen levels, and ovulatory dysfunction. Its etiology is multifactorial. Emerging evidence indicates that …

PurposeThis study aimed to investigate the impact of obstructive sleep apnea (OSA) on in vitro fertilization (IVF) and embryo transfer outcomes in infertile patients with polycystic ovary syndrome (PCOS).MethodsWe conducted a prospective ob…

OBJECTIVE: This study explores the metabolic profiles in the peripheral blood of infertile patients with adenomyosis (ADM) to identify key metabolites affecting pregnancy outcomes in these patients undergoing frozen embryo transfer (FET). O…

Menstruation is a key indicator of female reproductive health, yet clinical features and underlying mechanisms associated with menstrual changes following the coronavirus disease 2019 (COVID-19) infection remain unclear. Here, we recruited …

BackgroundTuberculosis can negatively impact both overall health and female reproductive function. This study investigated the relationship between the interferon-gamma release assay (IGRA) status and pregnancy outcomes in infertile women, …

BackgroundImbalances in alkali elements (AEs) and alkaline earth elements (AEEs) cause reproductive disorders. However, it remains unclear whether AEs/AEEs in follicular fluid have a relationship with the serious reproductive disorder known…

ObjectiveTo investigate the changes in bile acid (BA) metabolites within the follicular fluid (FF) of patients with diminished ovarian reserve (DOR) and to identify novel diagnostic markers that could facilitate early detection and interven…

BackgroundThe utilization of a double trigger, involving the co-administration of gonadotropin-releasing hormone agonist (GnRH-a) and human chorionic gonadotropin (hCG) for final oocyte maturation, is emerging as a novel approach in gonadot…

BackgroundThe effects of female chromosomal polymorphisms (FCPs) on various aspects of reproductive health have been investigated, yet the findings are frequently inconsistent. This study aims to clarify the role of FCPs on the outcomes of …

ObjectiveThis retrospective study aimed to assess the impact of hysteroscopic septum incision on in vitro fertilization (IVF) outcomes among infertile women diagnosed with a complete septate uterus and no history of recurrent pregnancy loss…

ObjectiveTo study the impact of congenital uterine anomalies on reproductive outcomes after in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI)-embryo transfer (ET).MethodsA retrospective study including a total of 865women…

BACKGROUND: Cumulative live birth rate (CLBR) is considered as the most important endpoint for assessing the probability of having a baby in a complete in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) treatment cycle. Many…

BackgroundEnsuring women's sexual and reproductive health (SRH) is a fundamental human right and key to 2030 agenda of the UN Sustainable Development Goals (SDGs), yet limited evidence exists on SRH in China, including national estimates an…

Due to the influence of economic, social and many other factors, there are more and more reproductive problems. Originally introduced for managing male factor infertility, intracytoplasmic sperm injection had become the most commonly used f…

Study questionTo construct prediction models based on the Bayesian network (BN) learning method for the probability of fertilization failure (including low fertilization rate [LRF] and total fertilization failure [TFF]) in assisted reproduc…