Background: Endometriosis is a common chronic gynecological disease associated with pain, impaired quality of life, reduced productivity, impaired fertility, and high healthcare costs. Diagnosis is often delayed because symptoms are normali…
Abstract Study question Are there differences at the molecular level in the most important genes of the mTOR/Akt-pathway in granulosa cells (GCs) of patients with or without endometriosis? Summary answer Our data show increased gene express…
Abstract Study question Can the endometrial proteomic signature be used as a minimally invasive biomarker to detect peritoneal endometriosis in women with dysmenorrhea? Summary answer Eutopic endometrial tissue from patients with peritoneal…
BACKGROUND: The pathogenesis of deep infiltrating endometriosis (DIE) is poorly understood. It is considered a benign disease but has histologic features of malignancy, such as local invasion or gene mutations. Moreover, it is not clear whe…
Zielsetzung Soziale Einflussfaktoren wie Unterstützung, aber auch Stress, können das Schmerzerleben entscheidend beeinflussen, wie Forschung z.B. bei chronischen Rückenschmerzen zeigen konnte. Gleichzeitig unterscheidet sich die neurale Sch…