Petra Brožič

No ORCID on file · 2 papers in corpus
article 2012
Expression of human aldo-keto reductase 1C2 in cell lines of peritoneal endometriosis: Potential implications in metabolism of progesterone and dydrogesterone and inhibition by progestins
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2011.12.011

The human aldo-keto reductase AKR1C2 converts 5α-dihydrotestosterone to the less active 3α-androstanediol and has a minor 20-ketosteroid reductase activity that metabolises progesterone to 20α-hydroxyprogesterone. AKR1C2 is expressed in dif…

other 2011
Selectivity and potency of the retroprogesterone dydrogesterone in vitro
Steroids ·doi:10.1016/j.steroids.2011.02.043

Dydrogesterone is widely used for menstrual disorders, endometriosis, threatened and habitual abortion and postmenopausal hormone replacement therapy. Although progestins have a promiscuous nature, dydrogesterone does not have clinically re…