Seki T

Transcriptomic classification methods have been proposed for ovarian clear cell carcinoma. However, their clinical significance and association with pathologically evaluated tumor-infiltrating lymphocytes (TILs) remain unclear. We establish…

AIM: Despite growing public attention toward infertility treatments and elective oocyte cryopreservation, awareness of fertility among young adults remains limited. Accurate knowledge of age-related fertility declines and ovarian reserve is…

The involvement of microbiota in the pathogenesis of endometriosis has been increasingly suggested; however, existing evidence remains inconsistent, largely owing to the challenges of analyzing extremely low-biomass samples. To clarify whet…

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common cause of irregular menstrual cycles and infertility. Current treatments primarily involve ovulation induction and sex steroid hormone therapy. Tokishakuyakusan (TSS) is a traditional …

BACKGROUND: Endometriosis is an estrogen-dependent chronic inflammatory disease, however the mechanisms underlying inflammation remain unclear. Non-hormonal drugs that can prevent endometriosis progression and resolve endometriotic infertil…

BACKGROUND: Endometriosis-associated ovarian cancer (EAOC) is a well-known type of cancer that arises from ovarian endometrioma (OE). OE contains iron-rich fluid in its cysts due to repeated hemorrhages in the ovaries. However, distinguishi…

A uterine artery pseudoaneurysm (UAP) can occur after a traumatic event to the uterus, and cause massive bleeding. A uterine manipulator has been widely used for gynecologic laparoscopic surgery as basically an atraumatic instrument. We des…

Matsushita, Mitsunobu MD; Nishio, Akiyoshi MD; Seki, Toshihito MD; Okazaki, Kazuichi MD Author Information