Silva S

ORCID: 0000-0002-1335-8648 · 4 papers in corpus
observational 2026
Attitudes of healthcare providers towards fertility preservation in Portugal: perceived support across indications and their ethical implications
BMC medical ethics ·doi:10.1186/s12910-026-01477-5

BACKGROUND: Healthcare providers (HCPs) play a pivotal role in shaping access to and ethical deliberation around fertility preservation. While fertility preservation due to oncological and non-oncological diseases is widely accepted, its us…

observational 2024
A real-world study of hereditary angioedema patients due to C1 inhibitor deficiency treated with danazol in the Brazilian Public Health System
Frontiers in medicine ·doi:10.3389/fmed.2024.1343547

INTRODUCTION: Hereditary angioedema (HAE) due to C1 inhibitor (C1-INH) deficiency is an ultra-rare autosomal dominant inherited disease that affects 1 in 67,000 people in the world. The attacks are based on subcutaneous and submucosal edema…

lab-animal 2013
Dysregulation of protease and protease inhibitors in a mouse model of human pelvic organ prolapse
PloS one ·doi:10.1371/journal.pone.0056376

Mice deficient for the fibulin-5 gene (Fbln5(-/-)) develop pelvic organ prolapse (POP) due to compromised elastic fibers and upregulation of matrix metalloprotease (MMP)-9. Here, we used casein zymography, inhibitor profiling, affinity pull…

observational 2012
High throughput, cell type-specific analysis of key proteins in human endometrial biopsies of women from fertile and infertile couples
Human reproduction (Oxford, England) ·doi:10.1093/humrep/der436

BACKGROUND: Although histological dating of endometrial biopsies provides little help for prediction or diagnosis of infertility, analysis of individual endometrial proteins, proteomic profiling and transcriptome analysis have suggested sev…