Meng-Jie Yang

No ORCID on file · 3 papers in corpus
lab-animal 2026
Exosomal miR-21-5p from ectopic endometrial stromal cells drives fibrosis progression in endometriosis through direct VHL targeting
Human cell ·doi:10.1007/s13577-026-01438-5

Ovarian endometriosis is a chronic inflammatory disease characterized by extensive tissue remodeling and fibrosis, which significantly impacts female reproductive health. This study demonstrates that ectopic endometrium (Ect) in patients wi…

lab-animal 2025
A novel mechanism of FTO modulating the progression of endometriosis through mediating the m6A methylation of GEF-H1 in a YTHDF1-dependent manner
Molecular medicine (Cambridge, Mass.) ·doi:10.1186/s10020-025-01130-8

BACKGROUND: Endometriosis (EMs) is a condition characterized by the growth of endometrial tissue outside the uterine cavity. Although this condition is benign, it has cancer-like features. N6-methyladenosine (m6A) is a common RNA modificati…

lab-animal 2024
The dysfunction of CD8+ T cells triggered by endometriotic stromal cells promotes the immune survival of endometriosis
Immunology ·doi:10.1111/imm.13786

Endometriosis is defined as an oestrogen-dependent and inflammatory gynaecological disease of which the pathogenesis remains unclear. This study aimed to investigate the cellular heterogeneity and reveal the effect of CD8+ T cells on the pr…