microRNAs (miRNAs) are small, non-coding RNAs which regulate gene expression at the posttranscriptional and translational level. Due to their high regulatory capacity, they are capable of modulating a variety of physiological and pathophysi…
BACKGROUND Mechanisms underlying early reproductive loss in the human are beginning to be elucidated. The migratory and invasive capacity of human endometrial stromal cells (ESCs) is increasingly recognized to contribute to the intense tiss…
The success of normal pregnancy depends on the protection, controlled invasion, and growth of the semiallogenic placenta within the maternal uterine environment. In the endometrium, the maternal response to pregnancy is characterized by inf…
Prolactin (PRL) secretion and PRL mRNA expression in human myometrial explant cultures was inhibited by the addition of human placental conditioned medium (HPCM). After 3 days treatment with 5% HPCM PRL secretion was reduced to 24% of contr…