Kohan L

No ORCID on file · 2 papers in corpus

2019

Analysis of polymorphisms, promoter methylation, and mRNA expression profile of maternal and placental P53 and P21 genes in preeclamptic and normotensive pregnant women.

Journal of Biomedical Science ·doi:10.1186/s12929-019-0586-x

BackgroundPreeclampsia (PE), as a multisystem disorder, is associated with maternal hypertension and proteinuria. Apoptosis seems to be involved in the pathophysiology of PE, although its precise pathogenic mechanisms are not well establish…

article 2017

mir-126 rs4636297 and TGF β RI rs334348 functional gene variants are associated with susceptibility to endometriosis and its severity

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590.2017.1290064

microRNAs (miRNAs) are negative regulators in a variety of cellular processes that occur in endometriosis. Therefore, functional polymorphisms in miRNA and miRNA binding sites may affect gene expression and contribute to susceptibility of e…