Kaikai Chang

No ORCID on file · 4 papers in corpus
article 2024
Extracellular succinate derived from ectopic milieu drives adhesion and implantation growth of ectopic endometrial stromal cells via the SUCNR1 signal in endometriosis
Cell communication and signaling : CCS ·doi:10.1186/s12964-023-01415-7

BACKGROUND: As a dual-function metabolite, succinate has emerged in cell function and plays a key signaling role in linking mitochondrial function to other cellular functions. Succinate accumulation in the cytoplasm is commonly associated w…

article 2024
Intraoperative dual laparoscopy and neo-rectoscopy for precise excision of bowel endometriosis
Endoscopy ·doi:10.1055/a-2440-6251
article 2024
The IL-33-ST2 axis plays a vital role in endometriosis via promoting epithelial-mesenchymal transition by phosphorylating β-catenin
Cell communication and signaling : CCS ·doi:10.1186/s12964-024-01683-x

OBJECTIVES: Interleukin 33 (IL-33) is a crucial inflammatory factor that functions as an alarm signal in endometriosis (EMs). Epithelial-mesenchymal transition (EMT), a process related to inflammatory signals, intracellular reactive oxygen …

article 2023
Distinct subtypes of endometriosis identified based on stromal-immune microenvironment and gene expression: implications for hormone therapy
Frontiers in immunology ·doi:10.3389/fimmu.2023.1133672

BACKGROUND: Endometriosis (EMs) is a chronic inflammatory condition that is highly heterogeneous. Current clinical staging fails to accurately predict drug responses and prognosis. In this study, we aimed to reveal the heterogeneity of ecto…