Kaikai Chang

No ORCID on file · 5 papers in corpus
lab-animal 2024
Extracellular succinate derived from ectopic milieu drives adhesion and implantation growth of ectopic endometrial stromal cells via the SUCNR1 signal in endometriosis
Cell communication and signaling : CCS ·doi:10.1186/s12964-023-01415-7

BACKGROUND: As a dual-function metabolite, succinate has emerged in cell function and plays a key signaling role in linking mitochondrial function to other cellular functions. Succinate accumulation in the cytoplasm is commonly associated w…

other 2024
Intraoperative dual laparoscopy and neo-rectoscopy for precise excision of bowel endometriosis
Endoscopy ·doi:10.1055/a-2440-6251
lab-animal 2024
The IL-33-ST2 axis plays a vital role in endometriosis via promoting epithelial-mesenchymal transition by phosphorylating β-catenin
Cell communication and signaling : CCS ·doi:10.1186/s12964-024-01683-x

OBJECTIVES: Interleukin 33 (IL-33) is a crucial inflammatory factor that functions as an alarm signal in endometriosis (EMs). Epithelial-mesenchymal transition (EMT), a process related to inflammatory signals, intracellular reactive oxygen …

other 2023
Distinct subtypes of endometriosis identified based on stromal-immune microenvironment and gene expression: implications for hormone therapy
Frontiers in immunology ·doi:10.3389/fimmu.2023.1133672

BACKGROUND: Endometriosis (EMs) is a chronic inflammatory condition that is highly heterogeneous. Current clinical staging fails to accurately predict drug responses and prognosis. In this study, we aimed to reveal the heterogeneity of ecto…

lab-animal 2016
DNA methylation promotes paired box 2 expression via myeloid zinc finger 1 in endometrial cancer
Oncotarget ·doi:10.18632/oncotarget.12626

This work investigated the role of paired box 2 (PAX2) in endometrial cancer and its epigenetic regulation mechanism. Endometrial cancer tissues and cell lines exhibited increased PAX2 expression compared with hyperplasia, normal endometriu…