Huang Q

BackgroundProlonged immobilization in patients with severe acute pancreatitis (SAP) leads to profound physical deconditioning, yet structured rehabilitation protocols remain underexplored in this population.ObjectiveTo investigate the effec…

Endometriosis (EM) affects approximately 10% of women of reproductive age and remains a prevalent estrogen-dependent gynecological disorder with limited therapeutic efficacy and high recurrence rates. Ferroptosis-an iron-dependent, non-apop…

BACKGROUND: The optimal luteinizing hormone (LH) concentration on the day of hCG trigger during long-protocol IVF/ICSI remains uncertain. Although some studies associate profound LH suppression with impaired reproductive outcomes, others re…

Endometriosis is a hormone-dependent chronic inflammatory disease associated with pain and infertility, remains diagnostically and therapeutically challenging due to its multifactorial nature. Molecular mechanisms of the dynamic changes dur…

BACKGROUND: Tumor necrosis factor (TNF) plays a prominent role in endometriosis research, but the evolution and current status of this field have not been systematically mapped. METHODS: This bibliometric study systematically analyzed publ…

BACKGROUND: Chronic endometritis (CE) is an inflammatory condition characterized by endometrial plasmacyte infiltration. The diagnosis and treatment of CE have attracted more and more attention. This article aimed to analyze the relevant ke…

Angiogenesis is critical from early development through the progression of life-threatening diseases. In rheumatoid arthritis (RA), angiogenesis is markedly heightened and undergoes aberrant changes that exacerbate the progression of synovi…

BACKGROUND: Hyperuricemia (HUA) impairs sperm function via oxidative stress and metabolic dysregulation. This retrospective cohort study aimed to investigate the therapeutic effect of density gradient centrifugation (DGC) on HUA-associated …

Ovarian clear cell carcinoma (OCCC) represents a rare and aggressive subtype of epithelial ovarian cancer with distinctive clinical and molecular characteristics. However, the identification, origin, and molecular features of the malignant …

BACKGROUND: Gasless transvaginal natural orifice transluminal endoscopic surgery (G-vNOTES) can avoid complications related to pneumoperitoneum, but there is limited research on G-vNOTES. Here, we aimed to compare the hemodynamic profiles a…

BACKGROUND: Endometriosis is a major contributor to infertility and pelvic pain, which brings a significant burden on family and society. Although the data of endometriosis in Global Burden of Disease (GBD) 2019 was reviewed, no updated ana…

OBJECTIVE: IVF/ICSI is associated with an increased risk of placenta accreta spectrum disorders (PAS). Invasive PAS can result in significant adverse maternal and fetal outcomes. This study investigates the impact of IVF/ICSI on the severit…

OBJECTIVE: To evaluate the effect of prior uterine cavity procedures on clinical and neonatal outcomes in patients undergoing first-time in vitro fertilization-embryo transfer with donor sperm (IVF-ET with DS). METHODS: This retrospective …

BACKGROUND: Oil-based contrast medium in hysterosalpingography has been recommended as an approach to improve fertility in recent years. However, this approach has rarely been applied to patients with unknown recurrent implantation failure …

RESEARCH QUESTION: Can machine learning models accurately predict the risk of early miscarriage following single vitrified-warmed blastocyst transfer (SVBT)? DESIGN: A dual-center retrospective analysis of 1,664 SVBT cycles, including 308 …

RationaleThis study aims to highlight the diagnostic challenges and multidisciplinary management of pelvic lipomatosis (PL), emphasizing imaging's pivotal role and the need for early intervention to mitigate long-term morbidity. With fewer …

BACKGROUND: Relugolix offers a promising alternative for endometriosis-associated pain, yet its comprehensive impact on health-related quality of life (HRQoL), particularly as measured by the disease-specific EHP-30 questionnaire, remains u…

Endometriosis involves ectopic growth of endometrial-like tissue, yet the spatial transcriptomic and metabolic landscape of ovarian endometriomas remains poorly understood. This investigation presents a comprehensive multi-omics analysis of…

Mesenchymal cells constitute the primary structural support elements within endometriotic lesions, yet their pivotal roles in endometriotic pathogenesis remain largely uncharted. This study aimed to construct a single-cell atlas of endometr…

PurposeThis study aimed to develop a predictive model for assessing clinical pregnancy probabilities in patients undergoing frozen-thawed cycles with single Day 6 blastocyst transfers.MethodsWe conducted a two-center retrospective cohort st…

BACKGROUND: Evidence indicates that the risk of developing a secondary ovarian cancer (OC) is correlated with estrogen receptor (ER) status. However, the clinical significance of the relationship between ER-associated breast cancer (BC) and…

Transfer RNA-derived small RNAs (tsRNAs), a recently identified subclass of small non-coding RNAs (sncRNAs), emerge through the cleavage of mature transfer RNA (tRNA) or tRNA precursors mediated by specific enzymes. The tumor necrosis facto…

RESEARCH QUESTION: Does the observed correlation between dyslipidaemia and endometriosis indicate a bidirectional causal association? DESIGN: Bidirectional Mendelian randomization was used to investigate the causal association between lipi…

BACKGROUND: This study investigates the potential impact of high progesterone (P) level on the day following human chorionic gonadotropin (HCG) injection on the clinical pregnancy outcomes of in vitro fertilization-embryo transfer (IVF-ET).…