Xiaofang Guo

No ORCID on file · 6 papers in corpus
lab-animal 2025
Increased HSD11β1 Expression in Human Leiomyomatous Uteri: Implication for Enhanced Glucocorticoid Signaling
The Journal of clinical endocrinology and metabolism ·doi:10.1210/clinem/dgaf255

CONTEXT: FK506-binding-protein-51 (FKBP51) is a glucocorticoid-induced co-chaperone protein previously shown to bind glucocorticoid receptor (GR), inhibiting its transcriptional activity. We previously found increased FKBP51 levels in uteri…

lab-animal 2024
Dysregulated expression of GATA2 and GATA6 transcription factors in adenomyosis: implications for impaired endometrial receptivity
F&S science ·doi:10.1016/j.xfss.2023.11.003

OBJECTIVE: To study the effect of adenomyosis on the localized expression of the GATA binding proteins 2 and 6 (GATA2 and GATA6) zinc-finger transcription factors that are involved in proliferation of hematopoietic and endocrine cell lineag…

2023
IN-VITRO GATA2 OVEREXPRESSION REVERSES DECIDUALIZATION DEFECTS BY IMPROVING ENDOMETRIAL RECEPTIVITY MARKERS IN HUMAN ENDOMETRIAL STROMAL CELLS FROM PATIENTS WITH ADENOMYOSIS
·doi:10.1016/j.fertnstert.2023.08.489
2022
DYSREGULATED GATA2 AND GATA6 TRANSCRIPTION FACTOR EXPRESSION IN PATIENTS WITH ADENOMYOSIS: IMPLICATIONS FOR IMPAIRED ENDOMETRIAL RECEPTIVITY
·doi:10.1016/j.fertnstert.2022.08.581
lab-animal 2020
Catecholestradiol Activation of Adrenergic Receptors Induces Endometrial Cell Survival via p38 MAPK Signaling
The Journal of clinical endocrinology and metabolism ·doi:10.1210/clinem/dgaa866

CONTEXT: Enhanced levels of catecholestradiols, 2-hydroxyestradiol (2-OHE2) or 4-hydroxyestradiol (4-OHE2), are reported in endometriosis. During gestation, catecholestradiol activation of adrenergic receptors (AR) elevates estrogen recepto…

2019
Propranolol inhibits catecholestrogen-induced human endometrial stromal cell survival mediated by p38 MAPK signaling: potential therapy for endometriosis
·doi:10.1016/j.fertnstert.2019.07.943