BackgroundGenetic polymorphisms in the luteinizing hormone (LH) β-subunit gene have been associated with responses to controlled ovarian hyperstimulation (COH) in in vitro fertilisation (IVF) patients. Variants in rs1800447 and rs34349826 m…
Menstrual blood flow is reversed through the fallopian tubes during the menstrual process and implants outside the uterus, which is the theory of pathogenesis in endometriosis sufferers. This study aims to analyze the level of DNA methylati…
OBJECTIVE: Endometriosis diagnostic delays are still encountered due to the lack of a reliable, noninvasive diagnostic test. Besides, menstrual blood is a relatively untapped field for diagnostics, yet it provides a readily accessible sourc…
OBJECTIVES: Endometriosis is a common gynecological disease with a significant economic burden. Growing evidence has suggested the role of aberrant gene expression and epigenetic mechanisms in the pathogenesis of endometriosis. This study a…
Abstract Objectives: Endometriosis is a common gynecological disease with a significant economic burden. Growing evidence has suggested the role of aberrant gene expression and epigenetic mechanisms in the pathogenesis of endometriosis. Th…
Abstract Diagnosis of endometriosis remains challenging, as the diagnostic delay is still encountered. This phenomenon is in accordance with the reported cases, in which the definitive diagnosis is approximately issued by 7—12 years delaye…
OBJECTIVE: Endometriosis is a multifactorial disease that affects 10% of women of childbearing age. Its development is known to be related to the MMP-2 gene. Specifically, the expression of MMP-2 is increase in endometriosis. The aim of thi…