Al-Hendy A

No ORCID on file · 52 papers in corpus

lab-animal 2008

Toward gene therapy of endometriosis: transductional and transcriptional targeting of adenoviral vectors to endometriosis cells

American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2008.01.059

OBJECTIVE: The purpose of this study was to screen a panel of targeted adenoviruses as vectors for endometriosis gene therapy. STUDY DESIGN: Endometriotic cells were obtained from subjects with ovarian endometriomas. Liver tissues were tak…

lab-animal 2007

Toward gene therapy of endometriosis: adenovirus-mediated delivery of dominant negative estrogen receptor genes inhibits cell proliferation, reduces cytokine production, and induces apoptosis of endometriotic cells

Fertility and sterility ·doi:10.1016/j.fertnstert.2006.11.046

OBJECTIVE: To use dominant negative mutants of estrogen receptor genes delivered to endometriosis cells via an adenovirus vector (Ad-DN-ER) to abrogate estrogen action on these cells. DESIGN: Experimental in vitro study. SETTING: Universi…