Orvis GD

No ORCID on file · 3 papers in corpus
lab-animal 2013
Cancer research ·doi:10.1158/0008-5472.can-13-0241

Endometrial cancer is preceded by endometrial hyperplasia, unopposed estrogen exposure, and genetic alterations, but the precise causes of endometrial cancer remain uncertain. Mig-6, mainly known as a negative regulator of the EGF receptor,…

lab-animal 2012
PloS one ·doi:10.1371/journal.pone.0044285

Endometrium is the inner lining of the uterus which is composed of epithelial and stromal tissue compartments enclosed by the two smooth muscle layers of the myometrium. In women, much of the endometrium is shed and regenerated each month d…

lab-animal 2010
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.1013226107

Female fertility requires estrogen to specifically stimulate estrogen receptor α (ERα)-dependent growth of the uterine epithelium in adult mice, while immature females show proliferation in both stroma and epithelium. To address the relativ…