Van Sinderen M

No ORCID on file · 4 papers in corpus
2024
Dysregulated miR-124-3p in endometrial epithelial cells reduces endometrial receptivity by altering polarity and adhesion.
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2401071121

The endometrium undergoes substantial remodeling in each menstrual cycle to become receptive to an implanting embryo. Abnormal endometrial receptivity is one of the major causes of embryo implantation failure and infertility. MicroRNA-124-3…

2019
miR-29c overexpression and COL4A1 downregulation in infertile human endometrium reduces endometrial epithelial cell adhesive capacity in vitro implying roles in receptivity.
Scientific reports ·doi:10.1038/s41598-019-45155-6

The endometrium is a highly complex tissue that is vulnerable to subtle gene expression changes and is the first point of contact for an implanting blastocyst. Successful blastocyst implantation can only occur when the endometrium is recept…

2019
Restoration of microRNA-29c in type I endometrioid cancer reduced endometrial cancer cell growth.
Oncology letters ·doi:10.3892/ol.2019.10588

Endometrial cancer is the most common gynaecological cancer worldwide, and the prognosis of patients with advanced disease remains poor. MicroRNAs (miRs) are dysregulated in endometrial cancer. miRs-29-a, -b and -c expression levels are dow…

2018
Galectin-7 is elevated in endometrioid (type I) endometrial cancer and promotes cell migration.
Oncology letters ·doi:10.3892/ol.2018.9193

Endometrial cancer (EC) is the most commonly diagnosed gynecological malignancy in Australian women. Notably, its incidence and mortality rate is increasing. Despite this, there are limited treatment options for EC. Galectin-7 regulates tum…