{"paper_id":"fcc2984f-6e8d-47ac-8b77-76d3846ed93b","body_text":"Abstract\nIntroduction and hypothesis\nUrinary retention after radical laparoscopic surgery for severe endometriosis is a clinically relevant complication. We hypothesized a relationship between the amount of resected nerves and the occurrence of urinary retention.\nMethods\nWe evaluated, retrospectively, a cohort of 221 patients. The expression of nerves in the resected specimens was investigated in patients with urinary retention and matched controls using standardized immunohistochemistry techniques.\nResults\nThe prevalence of urinary retention was 4.6% (n = 10). Importantly, there was no difference between cases and controls regarding the quantity of nerves in the resected specimens. The cumulative probability of 50% to overcome urinary retention was reached after 5.6 months. Age was the main risk factor for persistent retention (40.3 years with vs. 31.6 years without, p = 0.01).\nConclusions\nIn older endometriosis patients, surgical radicality should be balanced against preservation of organ function. There is a fairly good chance to recover, even after 6 months, which is important for patient counseling.\nSimilar content being viewed by others\nReferences\nMarpeau O, Thomassin I, Barranger E et al (2004) Laparoscopic colorectal resection for endometriosis: preliminary results. J Gynecol Obstet Biol Reprod (Paris) 33(7):600–606\nVolpi E, Ferrero A, Sismondi P (2004) Laparoscopic identification of pelvic nerves in patients with deep infiltrating endometriosis. Surg Endosc 18:1109–1112\nDonnez J, Squifflet J (2010) Complications, pregnancy and recurrence in a prospective series of 500 patients operated on by the shaving technique for deep rectovaginal endometriotic nodules. Hum Reprod 25(8):1949–1958\nCampagnacci R, Perretta S, Guerrieri M et al (2005) Laparoscopic colorectal resection for endometriosis. Surg Endosc 19(5):662–664\nDubernard G, Rouzier R, David-Montefiore E, Bazot M, Daraï E (2008) Urinary complications after surgery for posterior deep infiltrating endometriosis are related to the extent of dissection and to uterosacral ligaments resection. J Minim Invasive Gynecol 15(2):235–240\nNassif J, Trompoukis P, Barata S et al (2011) Management of deep endometriosis. RBM. doi:10.1016/j.rbmo:2010:08:012\nHockel M, Konerding MA, Heussel CP (1998) Liposuction-assisted nerve sparing extended radical hysterectomy: oncologic rationale, surgical anatomy and feasibility study. Am J Obstet Gynecol 178:971–976\nQuerleu D, Narducci F, Poulard V et al (2002) Modified radical vaginal hysterectomy with or without laparoscopic nerve-sparing dissection: a comparative study. Gynecol Oncol 85:154–158\nPossover M, Schneider A (2002) Slow-transit constipation after radical hysterectomy type III. Surg Endosc 16:847–850\nPossover M, Stober S, Plaul K, Schneider A (2000) Identification and preservation of the motoric innervation of the bladder in radical hysterectomy type III. Gynecol Oncol 79:154–157\nKovoor E, Nassif J, Miranda-Mendoza I, Lang-Avérous G, Wattiez A (2010) Long-term urinary retention after laparoscopic surgery for deep endometriosis. Fertil Steril 95(2):803e9\nVan Langendonckt A, Punyadeera C, Kamps R et al (2007) Identification of novel antigens in blood vessels in rectovaginal endometriosis. Mol Hum Reprod 13(12):875–886\nMinelli L, Fanfani F, Fagotti A et al (2009) Laparoscopic colorectal resection for bowel endometriosis; feasibility, complications, and clinical outcome. Arch Surg 144:234–239\nAcknowledgments\nWe thank Dr. Eberst (Hautepierre Hospital, Strasbourg, France) for his support with the urodynamic investigation.\nConflicts of interest\nNone.\nAuthor information\nAuthors and Affiliations\nCorresponding author\nRights and permissions\nAbout this article\nCite this article\nGabriel, B., Nassif, J., Trompoukis, P. et al. Prevalence and outcome of urinary retention after laparoscopic surgery for severe endometriosis—does histology provide answers?. Int Urogynecol J 23, 111–116 (2012). https://doi.org/10.1007/s00192-011-1492-2\nReceived:\nAccepted:\nPublished:\nIssue date:\nDOI: https://doi.org/10.1007/s00192-011-1492-2","source_license":"CC0","license_restricted":false}